How to study medicinal chemistry for GPAT?
TLDRIn this informative video, the host Gandhi is joined by Mr. Shubham Roy, an expert in Pharmaceutical Chemistry with an All India Rank of 312 in GPAT and currently an Assistant Professor at BMS College of BBS Institute of Pharmaceutical and Allied Sciences in Greater Noida. They discuss strategies for effectively studying Medicinal Chemistry for the Graduate Pharmacy Aptitude Test (GPAT). Shubham emphasizes the importance of practice, correlating chemical structures with nomenclature, and understanding the functional groups and their positions. He also highlights the significance of organic chemistry and pharmacology as foundational knowledge for mastering medicinal chemistry. Recommended books include 'Organic Chemistry' by Morrison and Boyd, and for a deeper understanding, 'Wilson and Gisvold's Textbook of Organic Chemistry' or 'Patai's Chemistry of Functional Groups.' Shubham also touches on the possibility of excelling in GPAT even without focusing on medicinal chemistry, provided one has a strong grasp of organic chemistry. The video concludes with advice to subscribe to the channel and engage with the content.
Takeaways
- 📚 Practice is key: The more you practice drawing and understanding the structures of medicinal chemistry, the better you'll remember them.
- 🔗 Correlation is crucial: Link the structure with nomenclature to understand the scaffold and functional groups of a molecule.
- 🧠 Strength in organic chemistry: A strong foundation in organic chemistry is essential for excelling in medicinal chemistry.
- 💊 Importance of pharmacology: If you have a good grasp of pharmacology, it will aid in understanding the classification and mechanisms of drugs.
- 📈 Structure, synthesis, and SAR: Focus on these areas as they are the most important parts of medicinal chemistry.
- 📚 Recommended books: 'Organic Chemistry' by Morrison and Boyd, 'Wilson and Gisvold's Textbook of Organic Chemistry', and 'Patai's Chemistry of Functional Groups'.
- 🌟 CNS drugs: Pay special attention to the structure and nomenclature of heterocyclic compounds, as they are commonly found in CNS drugs.
- 🚫 Not just medicinal chemistry: It's possible to crack the GPAT without deep knowledge of medicinal chemistry, but a basic understanding is recommended.
- 📈 Start with organic chemistry: A strong base in organic chemistry is the starting point, and then you can build upon it with medicinal chemistry.
- 📚 Additional resources: Books like 'Cleared in One Shot' can also be helpful for those preparing for the GPAT.
- ✅ It's possible: Even without studying medicinal chemistry in-depth, it's possible to qualify for the GPAT with a good rank.
Q & A
What is the key to remembering medicinal chemistry concepts?
-The key to remembering medicinal chemistry concepts is practice. By repeatedly drawing and visualizing chemical structures and correlating them with their nomenclature, one can better remember the details of the structures, their functional groups, and their positions.
How does one's knowledge of organic chemistry impact their understanding of medicinal chemistry?
-A strong concept of organic chemistry is crucial for understanding medicinal chemistry. It provides the foundational knowledge required to grasp the structure, synthesis, and nomenclature of drugs, which are core components of medicinal chemistry.
What are some recommended books for studying medicinal chemistry?
-Some recommended books for studying medicinal chemistry include 'Organic Medicinal Chemistry' by Rangachari, 'Wilson and Gisvold's Textbook of Organic Medicinal Chemistry', and 'Pharmacochemistry' by Dr. A.K. Basak.
Can someone excel in GPAT without studying medicinal chemistry?
-It is possible to excel in GPAT without studying medicinal chemistry, as some individuals have qualified with good ranks without focusing on this subject. However, having a basic understanding of organic chemistry is suggested to ensure a well-rounded preparation.
What are some important topics in medicinal chemistry for GPAT?
-Important topics in medicinal chemistry for GPAT include the structure, synthesis, and nomenclature of drugs, with a particular focus on CNS drugs, heterocyclic compounds, and their influence on drug design.
What is the relationship between pharmacology and medicinal chemistry?
-Pharmacology and medicinal chemistry are related in that certain areas, such as the classification of drugs and the mechanism of action of drugs, are common to both fields. A strong foundation in pharmacology can aid in understanding parts of medicinal chemistry.
Why is organic chemistry considered a prerequisite for medicinal chemistry?
-Organic chemistry is considered a prerequisite for medicinal chemistry because it provides the necessary understanding of chemical structures and reactions that are fundamental to the study of drug design and synthesis in medicinal chemistry.
What are some frequently asked questions in the GPAT related to medicinal chemistry?
-Frequently asked questions in the GPAT related to medicinal chemistry often pertain to the structure and synthesis of CNS drugs, the nomenclature of heterocyclic compounds, and the structure-activity relationships of various drug classes.
How does the study of heterocyclic compounds benefit a student preparing for GPAT?
-The study of heterocyclic compounds is beneficial for a student preparing for GPAT because many drugs have a heterocyclic nature. Understanding the nomenclature and structure of these compounds can lead to a better grasp of medicinal chemistry topics.
What is the importance of structure-activity relationship (SAR) in medicinal chemistry?
-The structure-activity relationship (SAR) is important in medicinal chemistry as it helps in understanding how the structure of a drug molecule affects its biological activity, which is crucial for drug design and optimization.
What advice would you give to someone who is weak in organic chemistry but wants to prepare for GPAT?
-For someone who is weak in organic chemistry but wants to prepare for GPAT, it is advised to start by strengthening their understanding of organic chemistry. This foundational knowledge will make it easier to tackle medicinal chemistry and pharmacology topics.
Outlines
📚 Medicinal Chemistry Preparation for GPAT
In this first paragraph, Gandhi, the channel host, introduces the topic of preparing for medicinal chemistry as part of the Graduate Pharmacy Aptitude Test (GPAT). He is joined by Mr. Shubham Roy, an expert in pharmaceutical chemistry from Jamia Hamdard University, who secured an All India Rank of 312 in GPAT and is currently an assistant professor. The key points discussed include the importance of practice in remembering chemical structures and nomenclature, correlating structures with their names, understanding the scaffold and functional groups of the compounds, and the significance of organic chemistry knowledge for medicinal chemistry. The paragraph also emphasizes that a strong foundation in pharmacology can make medicinal chemistry easier. Recommended books for studying medicinal chemistry include 'Organic Medicinal Chemistry by O.P. Taneja' and for a deeper understanding, 'Wilson and Gisvold's Textbook of Organic Chemistry' or 'Patai's The Chemistry of Functional Groups.'
🔍 Organic Chemistry as a Foundation for Medicinal Chemistry
The second paragraph continues the discussion on preparing for GPAT with a focus on the relationship between organic chemistry and medicinal chemistry. It is emphasized that a solid understanding of organic chemistry is crucial before delving into medicinal chemistry. The paragraph also addresses the possibility of cracking the GPAT without studying medicinal chemistry, citing examples of individuals who have qualified with good ranks despite not studying this subject. However, it is suggested to at least grasp the basics of organic chemistry. The paragraph concludes by mentioning important synthesis topics from medicinal chemistry that are frequently asked in GPAT, such as synthesis related to CNS compounds like barbiturates and benzodiazepines, and the importance of understanding tetracycline and diabetic medications.
Mindmap
Keywords
💡Medicinal Chemistry
💡GPAT
💡Pharmaceutical Chemistry
💡All India Rank
💡Assistant Professor
💡Structure and Nomenclature
💡Organic Chemistry
💡Pharmacology
💡Structure Activity Relationship (SAR)
💡Heterocyclic Compounds
💡Tetracyclines and Benzodiazepines
Highlights
Practice is key to remembering medicinal chemistry structures.
Correlating structure with nomenclature is essential for understanding medicinal chemistry.
Having a strong concept in organic chemistry and pharmacology makes medicinal chemistry a bonus subject.
Important portions of medicinal chemistry include structure, synthesis, and SAR (Structure-Activity Relationship).
For a strong foundation in medicinal chemistry, one should start with organic chemistry.
Recommended books for medicinal chemistry include 'Organic Chemistry' by Morrison and Boyd, and 'Wilson and Gisvold's Textbook of Organic Chemistry'.
Important topics for GPAT include CNS drugs, heterocyclic compounds, and their nomenclature.
It is possible to crack GPAT without studying medicinal chemistry, but having a basic concept of organic chemistry is advised.
Common and frequently asked questions in GPAT often relate to tetracycline and benzodiazepines.
Shubham Roy, an assistant professor, emphasizes the importance of practice and understanding the structure of medicinal chemistry.
The scaffold of a structure and the position of functional groups are crucial for remembering medicinal chemistry.
If pharmacology is strong, it aids in understanding the classification and mechanism of drugs in medicinal chemistry.
The book 'Organic Chemistry' by Morrison and Boyd is considered sufficient for a comprehensive understanding of the subject.
Marshall and Welborn's 'Organic Chemistry' is another recommended resource for students.
The concept of organic chemistry is fundamental and should not be overlooked when preparing for GPAT.
Medicinal chemistry can be a bonus subject if one has a strong foundation in both organic chemistry and pharmacology.
The video provides insights into how to prepare for GPAT with a focus on medicinal chemistry.
Subscribing to the channel and engaging with the content can provide further insights into medicinal chemistry preparation.
Transcripts
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