Basics of Meta-Analysis

CONNECTING ASIA TV
30 Apr 202260:30
EducationalLearning
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TLDRDr. Muhammad Imran Qureshi introduces a workshop series on meta-analysis, a statistical method for combining results from multiple studies. Aimed at simplifying this complex method, the series covers the basics, importance across various fields, and steps involved in conducting a meta-analysis. The workshop also discusses the use of software for meta-analysis, specifically focusing on the 'meta-analysis with R' (metafor) package in R. Participants are guided on how to input data, interpret results, and understand concepts like effect size, fixed and random effects, and heterogeneity. The session concludes with an invitation for questions and a promise of further detailed sessions.

Takeaways
  • πŸ“š Dr. Muhammad Imran Kurashi introduces the meta-analysis series, aiming to simplify the complex method for both novices and those familiar with basic statistics.
  • πŸŽ“ Dr. Kurashi is the Founding Director of Connecting Asia, affiliated with the University of TSIDE, UK, and is involved with the Association of Professional Researchers and Academicians (OPERA) UK.
  • πŸ“ˆ The workshop series is an extension of previous sessions on systematic literature review, focusing on quantitative analysis and reporting results in various fields, including business and engineering.
  • πŸ” The importance of meta-analysis is emphasized for its ability to generalize findings across studies, identify true effects, and improve the precision of estimations.
  • πŸ“ The process of meta-analysis involves four main steps: conducting a systematic literature review (SLR), recording results from previous studies, calculating effect sizes, and interpreting the results.
  • πŸ”’ Meta-analysis requires a broader search than SLR, including unpublished materials, dissertations, and thesis databases, to account for all available evidence.
  • πŸ“‹ A key component of preparing for meta-analysis is creating a results sheet that records the correlation coefficients (r) and sample sizes (n) from each study.
  • πŸ“‰ Understanding effect size is crucial; it quantifies the magnitude of the relationship between variables, with larger effect sizes indicating stronger relationships.
  • 🀝 The workshop covers both fixed and random effects models in meta-analysis, explaining their use based on the homogeneity of the population and the source of variation.
  • πŸ› οΈ JMV (Joanna Briggs Institute Meta-Analysis) software is introduced as a user-friendly tool for conducting meta-analysis, simplifying the process with its interface and modules.
  • 🌐 The workshop concludes with a Q&A session, addressing questions about the applicability of meta-analysis to various data types and the inclusion criteria for studies in a meta-analysis.
Q & A
  • What is the purpose of the meta-analysis series presented by Dr. Muhammad Imran Kureshi?

    -The purpose of the meta-analysis series is to educate participants about meta-analysis, a complex method in research that combines the results of multiple studies to draw more generalizable conclusions. The series aims to simplify this method for those not familiar with statistics and to build upon the basics for those who are.

  • Who is Dr. Muhammad Imran Kureshi and what are his affiliations?

    -Dr. Muhammad Imran Kureshi is the Founding Director of Connecting Asia, working at the University of T, Side, UK, and is associated with the Association of Professional Researchers and Academician (OPERA) UK. He is also an editor of the Journal of Management in 4N, as well as the Journal of Systematic Literature Review and Meta-Analysis.

  • What are the prerequisites for understanding meta-analysis according to the workshop?

    -The prerequisites for understanding meta-analysis include having a basic understanding of statistics and familiarity with systematic literature review, as the workshop builds upon the knowledge gained from previous workshops on systematic literature review.

  • What is the importance of meta-analysis in various fields of study?

    -Meta-analysis is important across various fields as it allows for the combination and summarization of results from multiple studies, providing a more precise estimation of effects and helping to identify true effects or relationships between variables. It is particularly useful in medicine but also applicable in business, engineering, and other disciplines.

  • How can one stay connected with Dr. Kureshi and his workshops?

    -To stay connected with Dr. Kureshi and his workshops, one can follow the community page on Facebook at facebook.com/review/slr, which is mentioned in the script for further engagement and updates.

  • What is the basic process involved in conducting a meta-analysis?

    -The basic process of conducting a meta-analysis involves four main steps: 1) Conducting a systematic literature review (SLR), 2) Recording results from previous studies, 3) Calculating the effect size, and 4) Interpreting the results. These steps help in understanding, quantifying, and generalizing the findings across studies.

  • What is the role of a systematic literature review (SLR) in meta-analysis?

    -A systematic literature review (SLR) is the first step in meta-analysis. It helps in identifying and compiling studies that are relevant to the research question, ensuring a comprehensive and unbiased selection of literature to be included in the meta-analysis.

  • What is the significance of calculating effect size in meta-analysis?

    -Calculating effect size in meta-analysis is significant as it provides a standardized measure of the strength and direction of the relationship between variables. This allows for the comparison and combination of results across different studies, leading to a summary effect size that can be interpreted more broadly.

  • What are the considerations when preparing a data sheet for meta-analysis?

    -When preparing a data sheet for meta-analysis, considerations include the type of analysis included in the studies, the type of data (nominal, ordinal, interval, ratio), the settings of the studies, and the purpose of the analysis. These factors are important for understanding the context and applicability of the results.

  • How can unpublished material and non-traditional sources be included in a meta-analysis?

    -Unpublished material and non-traditional sources such as thesis databases like ProQuest, preprints, and even rejected papers can be included in a meta-analysis by broadening the search criteria beyond just published works. This helps in capturing a more comprehensive view of the research landscape and addressing publication bias.

  • What is the difference between fixed effect and random effects models in meta-analysis?

    -Fixed effect models assume that the population is homogeneous and that the studies are estimating the same effect size, with any variation due to sample size. Random effects models, on the other hand, account for variability both within studies and between studies, assuming that the true effect size can vary across studies due to differences in populations, settings, or other factors.

  • How can software like 'jmovie' assist in conducting a meta-analysis?

    -Software like 'jmovie' simplifies the process of conducting a meta-analysis by providing a user-friendly interface to input data, select models (fixed or random effects), and run the analysis without needing to manually perform complex statistical calculations. It also helps in visualizing the results through forest plots and provides interpretation of the results.

  • What does the 'I^2' statistic represent in the context of meta-analysis?

    -The 'I^2' statistic represents the percentage of variation across studies that is due to heterogeneity rather than chance. An 'I^2' value greater than 80% typically indicates considerable heterogeneity, suggesting that a random effects model may be more appropriate than a fixed effect model for the meta-analysis.

  • Can meta-analysis be performed on qualitative data?

    -While meta-analysis is primarily quantitative, some forms of qualitative data can be included if they provide quantifiable results or can be converted into effect sizes. The key is to ensure that the data can be measured and compared across studies.

  • How does publication bias impact meta-analysis?

    -Publication bias can impact meta-analysis by skewing the results towards significant findings, as studies with non-significant results are less likely to be published. This can lead to an overestimation of the effect size. Researchers should attempt to include unpublished studies and use methods to assess and adjust for potential publication bias.

Outlines
00:00
πŸ“š Introduction to Meta-Analysis Workshop

Dr. Muhammad Imran Kurashi introduces the meta-analysis series, aiming to simplify the complex statistical method for both novices and those familiar with basic statistics. As the Founding Director of Connecting Asia and editor of the Journal of Management in 4N, he invites participants to engage through their website or social media. This workshop is an extension of previous ones, focusing on the basics of meta-analysis, a quantitative approach that requires understanding before using advanced software. The session will cover the fundamentals from a recommended textbook and address common struggles researchers face in writing meta-analysis papers.

05:01
πŸ” Understanding Meta-Analysis and Its Importance

The second paragraph delves into what meta-analysis entails, which is a quantitative analysis that combines results from previous studies to provide a summary effect. It highlights the importance of meta-analysis across various fields, including business and engineering, not just medicine. The paragraph explains that meta-analysis can improve the precision of estimations, highlight exact findings, and help in generalizing results across different studies. It also emphasizes the method's rigor and wide applicability, as well as its significance in publishing research in reputable journals.

10:02
πŸ“ Steps Involved in Conducting Meta-Analysis

This section outlines the four clear steps involved in conducting a meta-analysis: conducting a systematic literature review (SLR), recording results from previous studies, calculating the effect size, and interpreting the results. The paragraph emphasizes the importance of the SLR as the foundation for a meta-analysis and mentions the inclusion of various sources, such as unpublished material and theses. It also touches on the concept of publication bias and the need to include all forms of study results in a meta-analysis.

15:04
πŸ“‹ Preparing for Meta-Analysis: Defining Research Questions and Extracting Data

The focus shifts to preparing for a meta-analysis by defining a clear research question and identifying keywords. The process involves defining a search strategy and extracting data, with an emphasis on including different sources beyond published material. The paragraph also discusses the importance of preparing a result sheet that includes the correlation coefficient (r) and sample size (n), which are crucial for calculating effect sizes in meta-analysis.

20:05
πŸ“˜ Types of Data and Analysis in Meta-Analysis

This paragraph discusses the importance of considering the types of data and analysis included in the studies for a meta-analysis. It explains that different statistical tests, such as t-tests, chi-square, and ANOVA, can be used, but they must be converted into effect sizes for meta-analysis. The paragraph also mentions the importance of understanding the data type, whether binary, continuous, or correlational, as this influences the choice of effect size calculation.

25:07
πŸ”’ Effect Size Calculation and Types of Meta-Analysis

The concept of effect size is introduced as a quantitative measure of the magnitude of an experimental effect, indicating the strength of the relationship between variables. The paragraph explains how different types of data require different statistical treatments, such as log odds ratios for binary data or standardized mean differences for continuous data. It also introduces the terms 'fixed effect' and 'random effect' models in meta-analysis, which are crucial for understanding the variation between studies.

30:10
πŸ“Š Fixed and Random Effects Models in Meta-Analysis

This section clarifies the use of fixed and random effects models in meta-analysis. Fixed effects models are used when samples are drawn from a similar population, emphasizing studies with larger sample sizes. In contrast, random effects models account for variation between different populations or groups and are used when there is heterogeneity in the data. The paragraph also discusses the importance of sample size in determining the weight of a study's effect size in meta-analysis.

35:10
πŸ› οΈ Using Software for Meta-Analysis

The speaker introduces software tools used for conducting meta-analysis, such as Excel with add-ins like GEOMEAN and R. The paragraph focuses on the use of the JMEV software for meta-analysis, explaining how to install and run it for a fixed effects model. It provides a step-by-step guide on inputting data, selecting the appropriate module for meta-analysis, and interpreting the results presented by the software, including effect sizes and confidence intervals.

40:11
🌐 Addressing Heterogeneity and Moderator Variables in Meta-Analysis

The final paragraph addresses the issue of heterogeneity in meta-analysis and the use of moderator variables. It explains that heterogeneity can indicate that a random effects model is more appropriate than a fixed effects model. The paragraph also introduces the concept of moderator variables, which can be used to differentiate populations in a meta-analysis, and mentions that understanding whether these variables are dichotomous or continuous is crucial for proper analysis.

45:12
πŸ€” Closing Questions and Final Remarks

In the closing segment, the speaker opens the floor for questions, inviting participants to post their inquiries in the comment box for follow-up. The session concludes with a reminder to like, share, and subscribe for more content, emphasizing the value of the meta-analysis workshop as a starting point for further learning and exploration of the topic.

Mindmap
Keywords
πŸ’‘Meta-analysis
Meta-analysis is a research method that combines the results of multiple scientific studies to draw more general conclusions. It is a statistical technique that synthesizes findings across different studies to identify patterns and relationships. In the video, Dr. Muhammad Imran Kurashi discusses meta-analysis as a complex but powerful tool for summarizing and analyzing data from various research studies, emphasizing its importance in fields like medicine, business, and engineering.
πŸ’‘Systematic Literature Review (SLR)
A Systematic Literature Review is a comprehensive and structured approach to identifying, evaluating, and interpreting available research on a particular topic. In the context of the video, SLR is the first step in conducting a meta-analysis, where the researcher collects and critically assesses the existing literature to establish a solid foundation for further analysis.
πŸ’‘Effect Size
Effect size is a quantitative measure that indicates the strength or magnitude of a phenomenon being studied. It is used in meta-analysis to standardize the results across different studies and to calculate the overall impact of a variable on another. Dr. Kurashi explains that the main objective of meta-analysis is to calculate the effect size, which helps in determining the summary effect across all studies included in the analysis.
πŸ’‘Fixed Effect Model
The Fixed Effect Model is used in meta-analysis when the studies being analyzed are considered to be a random sample from a larger population with similar characteristics. It assumes that any variation between studies is due to sampling error. In the video, Dr. Kurashi mentions using the fixed effect model when the sample size plays a significant role in determining the effect size and when the studies are assumed to be from a similar population.
πŸ’‘Random Effect Model
The Random Effect Model, in contrast to the fixed effect model, accounts for variability both within studies and between studies. It is used when the studies are considered to be samples from a population of studies with varying true effects. The video script discusses the random effect model as an alternative to the fixed effect model when dealing with diverse populations or when there is significant heterogeneity among the studies.
πŸ’‘Heterogeneity
Heterogeneity in the context of meta-analysis refers to the degree of variation or differences between the studies that are being analyzed. It is an important consideration because it can affect the choice of model (fixed vs. random effects) and the interpretation of results. Dr. Kurashi points out that high heterogeneity (indicated by I-square values) might suggest the need for a random effects model over a fixed effect model.
πŸ’‘Publication Bias
Publication bias is a phenomenon where studies with significant or positive results are more likely to be published than those with non-significant or negative results. This can skew the findings of a meta-analysis. In the video, Dr. Kurashi briefly touches on the importance of including unpublished studies and considering publication bias to ensure a more comprehensive and unbiased meta-analysis.
πŸ’‘Forest Plot
A Forest Plot is a graphical representation used in meta-analysis to display the estimated effects and confidence intervals of individual studies, along with the combined effect size. It helps in visualizing the overall results and the relative contribution of each study. The video script mentions the forest plot as a tool to interpret the effect sizes and their significance in the meta-analysis.
πŸ’‘Jamovi Software
Jamovi is a statistical software that provides a user-friendly interface for conducting various statistical analyses, including meta-analysis. In the video, Dr. Kurashi demonstrates how to use Jamovi for conducting a meta-analysis, emphasizing its simplicity and effectiveness for researchers who may not be familiar with coding or more complex statistical software.
πŸ’‘Correlation Coefficient (r)
The correlation coefficient, often denoted as 'r', is a measure of the strength and direction of the relationship between two variables. In the context of the video, the correlation coefficient is used as a form of effect size in meta-analysis to quantify the relationship between variables such as salary and satisfaction across different studies.
Highlights

Introduction to the meta-analysis series by Dr. Muhammad Imran Kurashi, aimed at simplifying the complex method for those unfamiliar with statistics.

Dr. Kurashi's credentials and his involvement with the Association of Professional Researchers and Academician (OPERA) UK and the Journal of Management in 4N.

The workshop's focus on the basics of meta-analysis and its application beyond medicine to fields like business and engineering.

The importance of meta-analysis in combining results from multiple studies to find a summary effect size.

The four-step process of meta-analysis: conducting a systematic literature review, recording results, calculating effect size, and interpreting results.

The necessity of including both published and unpublished studies in a meta-analysis to account for publication bias.

How to prepare a result sheet for meta-analysis, focusing on recording correlation coefficients and sample sizes.

Different types of data and statistical tests relevant to meta-analysis, such as binary data, continuous data, and the use of effect sizes.

The significance of effect size in quantifying the magnitude of an experimental effect and its role in comparing group differences.

Understanding confidence intervals and their relationship with p-values in the context of meta-analysis.

The distinction between fixed effect and random effect models in meta-analysis and when to use each.

The use of software like JME (Joanna Briggs Institute Meta-Analysis) for conducting meta-analysis and its ease of use.

How to interpret results from meta-analysis software, including understanding effect sizes, confidence intervals, and heterogeneity statistics.

The importance of considering moderators in meta-analysis when there is a diverse population or settings involved in the studies.

Invitation for participants to ask questions and engage with the presenter for further clarification on meta-analysis concepts.

Final summary and invitation for further sessions to delve deeper into complex concepts and practical applications of meta-analysis.

Transcripts
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