Medical calculations, part 2, Veterinary Pharmacology

jennifer herndon
13 Jun 201611:35
EducationalLearning
32 Likes 10 Comments

TLDRIn this informative video, Dr. Herndon guides viewers through the process of calculating drug dosages for patients, emphasizing the importance of understanding the difference between 'dose' and 'dosage rate'. He explains how to use an animal's body weight, the drug dosage rate, and the drug concentration to determine the correct amount of medication to administer. The video also highlights the significance of accurately recording drug doses in medical records to ensure proper treatment and avoid confusion due to varying drug concentrations.

Takeaways
  • πŸ“ˆ Understanding the difference between 'dose' and 'dosage rate' is crucial; 'dose' refers to the quantity of the drug given at one time, while 'dosage rate' is the amount per unit of body weight, often provided in medical orders or drug labels.
  • πŸ“Š To calculate a drug dose, you need three key pieces of information: the patient's body weight, the drug dosage rate, and the drug concentration.
  • πŸ”„ When calculating with dosage rates, ensure that the units of body weight match the units used in the dosage rate (e.g., kilograms for mg/kg and pounds for mg/pound).
  • πŸ’Š The drug concentration can be found directly on the medication label and is essential for determining the amount of drug to administer.
  • πŸ§ͺ Dosage rates can also be based on body surface area (BSA), especially for chemotherapy drugs, which requires conversion from weight to BSA using a chart.
  • 🦴 Example calculation: For a 10 kg dog prescribed 10 mg/kg of clindamycin (25 mg/mL concentration), the dose is 100 mg, and the amount to administer is 4 mL.
  • πŸ• Another example: For a 40-pound dog with a 5 mg/pound order of amoxicillin (100 mg/tablet), the dose is 200 mg, and the amount to give is 2 tablets.
  • πŸ“‹ When recording drug information in medical records, always specify the dose of the active ingredient, not just the volume or number of units administered.
  • πŸ“š The video script serves as a comprehensive guide for medical professionals to understand and perform accurate drug dose calculations based on weight and concentration.
  • πŸ“ It is important to note that different formulations of the same drug can have different concentrations, so selecting the correct concentration is vital.
  • πŸŽ“ The video also emphasizes the importance of accurate documentation and communication of drug doses to ensure proper treatment and avoid medication errors.
Q & A
  • What are the three essential pieces of information required to calculate a drug dose?

    -The three essential pieces of information required to calculate a drug dose are the animal's body weight, the drug dosage rate, and the drug concentration.

  • What is the difference between the terms 'dose' and 'dosage' in the context of medical calculations?

    -In the context of medical calculations, a 'dose' refers to the quantity of the drug's active ingredient that is delivered to a patient at one particular time, while a 'dosage' is the amount of drug per unit of body weight, which is often provided in the veterinarian's orders, on the drug label, or in a drug formulary.

  • How is the drug dose calculated based on the given information?

    -The drug dose is calculated by multiplying the animal's body weight by the dosage rate of the drug.

  • What is the significance of drug concentration in drug administration?

    -Drug concentration is significant in drug administration as it determines the amount of the drug that needs to be given to deliver the calculated dose. It is used in the formula where the dose divided by the drug concentration equals the amount of the drug to be administered.

  • Where can the concentration of a drug be found?

    -The concentration of a drug can be found directly on the medication itself, on the label, or in some cases, in a drug formulary or reference guide.

  • What is the purpose of recording the drug dose in the patient's medical record?

    -Recording the drug dose in the patient's medical record ensures that there is a clear and accurate record of the amount of the active ingredient administered, which is crucial for tracking the patient's treatment and avoiding medication errors.

  • How can body surface area be used in calculating drug dosage instead of weight?

    -Body surface area can be used in calculating drug dosage, particularly for chemotherapy drugs, by first determining the animal's weight in kilograms, then using a conversion chart to find the corresponding body surface area in square meters. The dosage rate is then applied to this area rather than the weight to calculate the dose.

  • What is the importance of using the correct drug concentration when administering medication?

    -Using the correct drug concentration is crucial to ensure that the patient receives the appropriate dose of the active ingredient. Different formulations of the same drug can have different concentrations, and selecting the wrong one can lead to underdosing or overdosing.

  • How can one determine the drug concentration if it is not explicitly stated on the label?

    -If the drug concentration is not explicitly stated on the label, it can often be found in the drug's documentation, a drug formulary, or by contacting the manufacturer or a pharmacist for the specific information.

  • What is an example of a drug where the dosage rate is based on body surface area?

    -Vincristine sulfate, a chemotherapy drug, is an example where the dosage rate is given in mgs per meter squared rather than mgs per kilogram.

  • How should the administration of a drug be recorded in a patient's medical record?

    -The administration of a drug should be recorded in the patient's medical record by noting the date and time of administration, the specific treatment (including the drug name and dose amount), and the initials of the person who administered the medication. It is important to include the concentration of the drug to accurately reflect the dose given.

Outlines
00:00
πŸ“š Introduction to Drug Dosage Calculations

This paragraph introduces Dr. Herndon and the topic of medical calculations, specifically focusing on drug dosages. It emphasizes the importance of understanding the difference between 'dose' and 'dosage', and outlines the three key elements required for dosage calculations: animal's body weight, drug dosage rate, and drug concentration. The paragraph also explains how to obtain dosage rates from various sources such as veterinary orders, drug labels, or drug formularies. The main formula for calculating the dose is presented as the animal's body weight times the dosage rate of the drug. The importance of using consistent units in calculations is highlighted, and examples of different dosage rates (mg/kg, mg/pound, units/kg) are provided. The paragraph concludes with an introduction to the concept of drug concentration and its role in determining the administered amount of a drug.

05:03
πŸ§ͺ Calculation Examples and Drug Concentration

This paragraph delves into practical examples of drug dosage calculations, demonstrating how to calculate the correct amount of medication to administer based on the previously discussed formulas. It explains how to convert body weight to the appropriate units and how to use drug concentration to find the final administered amount. The paragraph uses examples with different drugs (clindamycin and amoxicillin) to illustrate the process, showing how to calculate the dose in milligrams and then determining the volume (in mls or tablets) to be given. It also touches on the concept of body surface area as an alternative to weight for certain drugs, particularly chemotherapy medications. The importance of accurate record-keeping in medical records is stressed, emphasizing the need to document the dose of the active ingredient rather than just the volume or form of the medication administered.

10:03
πŸ“‹ Proper Documentation of Medication Administration

The final paragraph focuses on the correct method of documenting medication administration in a patient's medical record. It provides a simplified medical treatment chart as an example, detailing the necessary information to be recorded such as the date and time of medication, the treatment itself, and the initials of the administering person. The paragraph emphasizes the importance of specifying the dose amount of the drug in milligrams or other appropriate units, rather than just the volume or form, to ensure clarity and continuity of care. It concludes the video script by directing viewers to take a quiz related to the topic, reinforcing the need for practice and understanding of the material covered.

Mindmap
Keywords
πŸ’‘Drug Dose
The term 'Drug Dose' refers to the specific quantity of an active pharmaceutical ingredient that is administered to a patient at one time. It is a central concept in the video, as the speaker explains how to calculate the appropriate dose based on the patient's body weight, the drug's dosage rate, and its concentration. For instance, the video provides an example of calculating a dog's dose of clindamycin as 100 milligrams, derived from the product of the dog's weight (10 kg) and the dosage rate (10 mg/kg).
πŸ’‘Body Weight
Body weight is a critical factor in determining the appropriate dosage of a drug for a patient. It is used in conjunction with the drug's dosage rate to calculate the drug dose. The video emphasizes the importance of accurate weight measurement, as it directly affects the calculation of the dose. For example, a 10 kg dog would have a different drug dose than a 40-pound dog.
πŸ’‘Drug Dosage Rate
The drug dosage rate is the amount of a drug to be given per unit of body weight, often expressed in milligrams per kilogram (mg/kg) or milligrams per pound. It is a standard measure provided in veterinary orders, drug labels, or pharmacopeias such as Plumb's. The dosage rate is a fundamental part of the calculation process for determining a patient's drug dose.
πŸ’‘Drug Concentration
Drug concentration refers to the amount of active drug ingredient present in a given volume of the drug solution or formulation. It is typically expressed in milligrams per milliliter (mg/mL) or milligrams per tablet. Concentration is necessary for determining the volume or number of units of a drug to be administered, based on the calculated dose.
πŸ’‘Dose Calculation
Dose calculation is the process of determining the appropriate amount of a drug to be administered to a patient based on their body weight, the drug's dosage rate, and its concentration. This calculation is essential for safe and effective medication administration, ensuring that the patient receives the correct therapeutic dose.
πŸ’‘Veterinary Orders
Veterinary orders are the specific instructions given by a veterinarian for the administration of medication to a patient. These orders include the drug's name, dosage rate, and often the drug concentration, which are crucial for accurate dose calculation and medication administration.
πŸ’‘Pharmaceutical Label
A pharmaceutical label is the information provided on the packaging of a medication, which includes details about the drug's concentration, instructions for use, and safety information. The label is essential for determining the drug concentration needed for dose calculation.
πŸ’‘Body Surface Area
Body surface area (BSA) is a measurement that is particularly used for dosage calculations of certain drugs, like chemotherapy medications. It is an estimate of the total surface area of a patient's body, typically expressed in square meters (mΒ²). BSA dosage rates are used when the drug distribution and metabolism are related to the patient's body size in a complex way, rather than just weight.
πŸ’‘Medical Record
A medical record is a documented account of a patient's medical history, including diagnoses, treatments, medications, and other relevant health information. In the context of the video, it is important to accurately record the drug dose in terms of the active ingredient in the medical record, rather than just the volume or number of units administered.
πŸ’‘Drug Formulations
Drug formulations refer to the different strengths or concentrations of the same medication that are available for use. These formulations are designed to provide flexibility in dosage and administration, catering to the varying needs of patients. The video highlights the importance of selecting the correct formulation when administering a drug.
πŸ’‘Chemotherapy Drugs
Chemotherapy drugs are medications used to treat cancer by destroying cancer cells. These drugs often have dosage rates based on body surface area rather than weight, as they need to reach a therapeutic level throughout the body. The video discusses the calculation of doses for chemotherapy drugs, such as vincristine sulfate, and the importance of accurate dosage for effective cancer treatment.
Highlights

The video is a part of a medical review series focusing on drug dosage calculations.

Three key elements are required for drug dosage calculations: animal's body weight, drug dosage rate, and drug concentration.

The difference between 'dose' and 'dosage' is clarified, with 'dose' being the quantity of the active ingredient delivered to a patient.

The dosage rate is typically provided and not calculated, found in veterinary orders, drug labels, or drug formularies.

The formula for calculating the drug dose is body weight times the dosage rate.

Unit consistency is crucial when calculating dosages, ensuring weight is in the correct unit (kg or lbs) for the dosage rate.

Drug concentration is found directly on the medication label and is essential for calculating the amount of drug to administer.

Different drug concentrations are highlighted by color-coding on drug bottles, signifying different formulations.

Examples are provided for calculating drug doses using different drugs (Antirobe Aquadrops and amoxicillin tablets) and their respective concentrations.

A method for calculating drug doses based on body surface area (in mgs per meter squared) is discussed, particularly for chemotherapy drugs.

Instructions are given for recording accurate drug dosages in medical records, emphasizing the importance of noting the active ingredient's quantity.

A simplified medical treatment chart is presented as an example of proper documentation, including date, drug treatment, and administration initials.

The video concludes with a prompt to take a quiz for further practice on the material covered.

The necessity of using the correct drug concentration when documenting dosages is stressed to avoid confusion and ensure accurate treatment.

The video provides a comprehensive guide for medical professionals to accurately calculate and document drug dosages for patients.

Practical applications of drug dosage calculations are demonstrated with real-world examples, enhancing understanding and usability.

The importance of precision and accuracy in medical calculations is emphasized to ensure patient safety and effective treatment.

Transcripts
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