Oral Bacteria And Your Health - with Dr. Mark Burhenne | The Empowering Neurologist EP. 162

The Empowering Neurologist with David Perlmutter, MD

17 Apr 202370:34

EducationalLearning

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TLDRIn this episode of the Empowering Neurologist podcast, Dr. David Perlmutter explores the critical connection between oral health and overall well-being, focusing on the oral microbiome. His guest, Dr. Mark Burhenna, a family and sleep medicine dentist, emphasizes the importance of a balanced oral microbiome for preventing diseases like Alzheimer's and discusses the role of specific bacteria, such as P. gingivalis, in systemic inflammation. They address the significance of proper oral care, the overuse of fluoride, and the need for interdisciplinary collaboration in healthcare to optimize patient outcomes.

Takeaways

🦠 The oral microbiome is a diverse and essential community of microorganisms that can impact overall health, including the risk of developing conditions like Alzheimer's and cardiovascular diseases.
🧠 There is a significant connection between oral health and brain health, with the presence of certain bacteria in the mouth potentially contributing to neurodegenerative diseases like Alzheimer's.
👄 The mouth is considered the 'headwaters' of the gut, indicating that what happens in the oral cavity can have downstream effects on the entire digestive system and beyond.
🔬 Research suggests that Porphyromonas gingivalis, a bacterium linked to gum disease, can affect the brain's amyloid and tau proteins, which are associated with Alzheimer's disease.
🌱 The health of the oral microbiome is influenced by diet and environmental factors, emphasizing the importance of a balanced intake and avoiding excessive sugars and carbohydrates.
🍽️ The concept of biofilm in the mouth is crucial for maintaining oral health; it serves as a protective layer and helps in remineralization, rather than being something to be completely eradicated.
🌿 The use of essential oils in toothpaste can be detrimental to the oral microbiome, as they have bactericidal properties that disrupt the balance of microorganisms.
🪥 The approach to oral care should focus on nourishing and maintaining the oral microbiome rather than aggressive cleaning, which can harm the beneficial bacteria.
💧 Fluoride, commonly added to toothpaste and water supplies, has been a subject of controversy due to potential negative health effects, including impacts on cognitive development.
🔬 Advances in oral microbiome testing can provide insights into individual oral health and systemic connections, emphasizing the need for collaboration between dental and medical professionals.

Q & A

What is the significance of the oral microbiome in relation to overall health?
-The oral microbiome plays a crucial role in overall health as it is linked to various chronic diseases, including Alzheimer's, diabetes, and coronary artery disease. It is considered the 'headwaters' of the gut and can influence systemic health through direct and indirect mechanisms.
How does periodontal disease relate to the risk of Alzheimer's disease?
-Periodontal disease has been found to have a connection with the risk of Alzheimer's disease. The bacteria involved in periodontal disease, such as P. gingivalis, can enter the bloodstream and affect the brain, potentially contributing to the development of Alzheimer's.
What is the role of P. gingivalis in gum disease and its potential impact on the brain?
-P. gingivalis is a key bacterium involved in gum disease and has been found in the brain. It can potentially contribute to Alzheimer's disease by inducing inflammation and affecting the processes related to amyloid plaque formation and tau protein phosphorylation.
Why is it important to maintain a balanced oral microbiome?
-Maintaining a balanced oral microbiome is important for preventing dysbiosis, where harmful bacteria can proliferate and cause oral diseases. A balanced oral microbiome can also support overall health by preventing the harmful effects of certain bacteria on systemic health.
How does the use of fluoride in toothpaste and water affect health?
-Fluoride is commonly added to toothpaste and water supplies for its cavity-fighting properties. However, there are concerns about its potential neurological effects, including impacts on cognitive development and brain function.
What are some of the misconceptions about the oral microbiome that the podcast aims to clarify?
-One misconception is that the oral microbiome should be sterilized or 'cleaned' with harsh chemicals. In reality, the oral microbiome is essential for health, and its balance should be maintained rather than destroyed.
What is the significance of biofilms in the mouth, and how should they be treated?
-Biofilms in the mouth are protective layers of bacteria that help remineralize teeth and perform other beneficial functions. They should not be eliminated but rather nourished and maintained in a healthy state.
How does diet affect the oral microbiome and, consequently, overall health?
-Diet has a significant impact on the oral microbiome. Consuming easily fermentable carbohydrates can lead to an imbalance, promoting the growth of harmful bacteria and potentially leading to oral and systemic health issues.
What are some of the emerging products or practices in oral care that support a healthy oral microbiome?
-Emerging products include toothpastes with hydroxyapatite and other remineralizing agents. Practices such as tongue scraping and the use of water picks are also gaining recognition for their ability to support oral health without disrupting the microbiome.
Why is there a push to remove or reduce fluoride in toothpaste and water supplies?
-The push to remove or reduce fluoride is due to growing evidence of its potential negative health effects, including cognitive impairment and other neurological issues. There is also a movement towards more natural and health-supporting oral care products.
What role does nitric oxide play in oral health and its connection to Alzheimer's disease?
-Nitric oxide, produced by certain bacteria in the mouth, has various health benefits, including immune functions and vasodilation. Its production can be compromised by the use of certain mouthwashes, potentially impacting overall health and the risk of Alzheimer's disease.

Outlines

00:00

😀 Introduction to the Podcast and the Importance of Oral Health

The podcast begins with an introduction to Dr. David Perlmutter, a neurologist, and the topic of oral health's connection to overall well-being. The guest, Dr. Mark Burhenna, is highlighted for his expertise in the mouth-body connection, particularly the oral microbiome's role in health. The discussion emphasizes the significance of oral bacteria in systemic health, including links to Alzheimer's and other diseases, and the importance of a balanced oral microbiome.

05:01

🌱 The Oral Microbiome and Its Impact on Systemic Diseases

This paragraph delves into the oral microbiome's diversity and its role in systemic diseases. It explains the connection between oral bacteria and chronic diseases, the potential for oral bacteria to affect mental health, and the emerging research on the oral microbiome's influence on the gut-brain axis. The conversation also touches on the bi-directional relationship between oral and gut health, including the impact of oral inflammation on systemic inflammation and disease.

10:02

🦠 The Role of P. gingivalis in Alzheimer's Disease

The script discusses the specific bacterium P. gingivalis, known for causing gum disease, and its potential link to Alzheimer's disease. It explores how this bacterium can enter the brain and contribute to the development of Alzheimer's by affecting amyloid plaques and tau protein. The paragraph also addresses the prevalence of gum disease and its potential as a risk factor for severe COVID-19 outcomes.

15:02

🧠 Alzheimer's Disease and the Oral Microbiome Connection

The focus shifts to the mechanisms by which oral health can influence Alzheimer's disease. It discusses the potential for poor oral health to contribute to brain inflammation and the accumulation of harmful amyloid proteins. The paragraph also highlights the importance of understanding the pathways through which oral bacteria can affect brain health and the need for further research in this area.

20:03

💧 The Importance of a Balanced Oral Microbiome

This section emphasizes the need to maintain a balanced oral microbiome rather than eliminating all bacteria. It discusses the role of biofilms in oral health, the benefits of certain mouth bacteria in producing nitric oxide, and the potential health implications of disrupting the oral microbiome with harsh chemicals or disinfectants.

25:05

🌿 The Role of Diet and Environment in Oral Health

The paragraph examines how diet and lifestyle factors can impact the oral microbiome's health. It discusses the importance of a balanced diet, the negative effects of sugar and carbohydrates on oral bacteria, and the role of the Western diet in contributing to oral health issues. It also touches on the importance of maintaining a healthy oral environment to prevent the overgrowth of harmful bacteria.

30:09

🪥 Oral Hygiene Practices and Their Impact on Health

This section discusses common oral hygiene practices and their potential impact on health. It questions the effectiveness of toothpastes containing sodium lauryl sulfate and the use of mouthwash, suggesting that these products may disrupt the oral microbiome. The paragraph also explores alternative oral care products and practices that may be more beneficial for maintaining a healthy oral environment.

35:11

🚫 The Controversy Surrounding Fluoride Use

The script addresses the ongoing debate about fluoride's role in dental care. It presents concerns about fluoride's potential negative effects on cognitive development and overall health, citing studies that link fluoride exposure to lower IQs in children. The paragraph also discusses the history of fluoride use and the current legal challenges against its addition to water supplies.

40:11

🔬 The Need for Scientific Research and Collaboration

The final paragraph calls for more scientific research and collaboration between medicine and dentistry. It stresses the importance of understanding the oral microbiome's role in systemic health and the need for healthcare professionals to work together to improve patient outcomes. The conversation concludes with a call to action for the medical community to embrace the oral health connection in their practices.

45:13

👋 Closing Remarks and Invitation for Future Discussions

In conclusion, the podcast host thanks the guest for the insightful discussion and emphasizes the importance of the oral microbiome in overall health. The host expresses anticipation for future conversations on the topic and invites listeners to explore the guest's website for more information, highlighting the value of the shared knowledge.

Mindmap

Keywords

💡Oral Microbiome

The oral microbiome refers to the diverse community of microorganisms that inhabit the human mouth, including bacteria, fungi, and viruses. It plays a critical role in maintaining oral health and is intricately linked to overall health as discussed in the video. The script emphasizes the importance of nurturing a balanced oral microbiome to prevent diseases like Alzheimer's and gum disease, highlighting the connection between oral health and systemic health.

💡Gut-Brain Axis

The gut-brain axis is a term used to describe the bidirectional communication system between the gastrointestinal tract and the central nervous system. In the script, it is mentioned to illustrate the broader concept of how different parts of the body, such as the gut and the oral cavity, can influence brain health. The discussion extends this concept to the oral microbiome, suggesting a similar 'oral-brain axis'.

💡Periodontal Disease

Periodontal disease, also known as gum disease, is an infection of the structures around the teeth, which can lead to tooth loss if left untreated. The video script discusses the connection between periodontal disease and an increased risk of systemic conditions like Alzheimer's and coronary artery disease, emphasizing the impact of oral health on overall health.

💡P. gingivalis

P. gingivalis, or Porphyromonas gingivalis, is a type of bacteria associated with gum disease. The script highlights research suggesting that this bacterium may have a connection to Alzheimer's disease, either through direct infection or by contributing to inflammation and other systemic effects that increase the risk of cognitive decline.

💡Inflammation

Inflammation is the body's natural response to harmful stimuli and is a key process in the development of many diseases. The video script discusses how inflammation in the mouth, particularly from periodontal disease, can have systemic effects, potentially contributing to conditions like Alzheimer's and heart disease.

💡Nitric Oxide

Nitric oxide is a molecule with various functions in the body, including as a signaling molecule in the nervous system and as a regulator of blood flow. The script mentions that the oral microbiome contributes to nitric oxide production, which is important for vascular health and may have implications for conditions like Alzheimer's disease.

💡Biofilm

A biofilm is a community of microorganisms attached to a surface and enclosed in an extracellular polymeric substance. In the oral cavity, biofilms are commonly known as dental plaque. The script explains that biofilms are not just harmful; they can also serve protective functions, such as aiding in the remineralization of teeth.

💡Remineralization

Remineralization is the process by which minerals, like calcium and phosphate, are redeposited into tooth enamel to repair early signs of decay. The video script discusses the importance of remineralization in maintaining oral health and how the oral microbiome and certain dietary components can support this process.

💡Fluoride

Fluoride is a mineral that is commonly added to toothpaste and drinking water to help prevent tooth decay. The script raises concerns about the use of fluoride, citing research that suggests it may have negative effects on cognitive development and overall health, and discussing the need for re-evaluation of its widespread use.

💡Dysbiosis

Dysbiosis refers to an imbalance in the microbial composition of an ecosystem, which can lead to disease. In the context of the video script, oral dysbiosis is linked to an overgrowth of harmful bacteria in the mouth, potentially contributing to periodontal disease and other health issues.

💡Functional Dentistry

Functional dentistry is an approach to dental care that considers the broader systemic effects of oral health on the body. The script mentions the importance of finding a dentist trained in functional dentistry, who understands the connections between oral health and systemic conditions, and can provide holistic care.

Highlights

The oral microbiome is crucial for overall health and can impact conditions like Alzheimer's and coronary artery disease.

Dr. David Perlmutter and Dr. Mark Burhenna discuss the importance of oral health in relation to systemic health.

Periodontal disease is linked to an increased risk of metabolic problems and chronic degenerative conditions.

The mouth is the beginning of the digestive system and its health is integral to general health.

Oral bacteria, particularly P. gingivalis, have been found in the brain and are associated with Alzheimer's disease.

The connection between oral health and brain health is significant, with inflammation being a key factor.

The oral microbiome's diversity and size are second only to the gut microbiome, emphasizing its importance.

Dysbiosis in the oral microbiome can lead to systemic inflammation and various chronic diseases.

Proper oral hygiene and a healthy diet are essential for maintaining a balanced oral microbiome.

Nitric oxide, produced by certain oral bacteria, plays a role in immune response and blood vessel dilation.

The use of abrasive toothpastes and mouthwashes can disrupt the beneficial functions of the oral microbiome.

Biofilms in the mouth serve a protective role and are involved in remineralization of teeth.

Disrupting the oral biofilm with harsh chemicals can lead to a more aggressive oral microbiome.

Tongue scraping can promote healthful nitric oxide production and decrease blood pressure.

The嘉宾 discusses the potential of hydroxyapatite in toothpaste as a nourishing alternative to fluoride.

Charcoal in toothpaste can adsorb stains but may be abrasive; the RDA index should be considered.

Sodium lauryl sulfate (SLS) in toothpaste can break down the oral mucosa and should be avoided.

The importance of cellular minerals like magnesium and boron for oral and overall health is highlighted.

The fluoride controversy and its potential neurological impacts are discussed, with a call for re-examination.

The upcoming lawsuit against the EPA regarding fluoride and its potential outcomes are mentioned.

The need for collaboration between medical and dental professions for holistic patient care is emphasized.

High-resolution oral microbiome testing is now available, offering insights into individual oral health.

The podcast concludes with a call to action for better integration of oral health in overall healthcare.

Transcripts

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Related Tags

Oral Microbiome Alzheimer's Risk Dental Health Systemic Wellness Gut-Brain Connection Mouth Health Inflammation Neurologist Podcast Healthcare Integration Disease Prevention