I Took 5 DNA Tests and Compared Them | Which One Is Best?

UsefulCharts
28 May 202123:15
EducationalLearning
32 Likes 10 Comments

TLDRIn this informative video, Matt Baker explores the world of DNA testing, comparing five different services: CircleDNA, FamilyTreeDNA, 23andMe, Ancestry.com, and MyHeritage. He discusses the cost, collection methods, and the type of information each test provides, ranging from health risks to ancestry details. CircleDNA offers comprehensive health insights, while FamilyTreeDNA is ideal for those seeking in-depth genealogical data. 23andMe and Ancestry.com focus on ancestry with added health reports, and MyHeritage provides a cost-effective option for ancestry research. The video also touches on the potential surprises and discoveries DNA tests can unveil, such as unknown relatives, and the importance of considering one's interests and needs when choosing a DNA testing service.

Takeaways
  • 🧬 DNA tests can be a valuable tool for those interested in genealogy and building their family trees.
  • 💰 There are various DNA tests available, each with different pricing and focuses, from health to ancestry.
  • 🔬 CircleDNA offers detailed health-related information and is marketed as the 'World’s Most Comprehensive DNA Test'.
  • 📦 Most DNA test kits require either a cheek swab or saliva sample, and have specific instructions to ensure accurate results.
  • ⏱ Waiting time for DNA test results can be several weeks, as the company needs time to analyze the sample and prepare the report.
  • 📊 CircleDNA provides a comprehensive health risk assessment for hereditary cancers and other conditions, along with ancestry information.
  • 👪 FamilyTreeDNA offers autosomal DNA testing, and more detailed reports on mitochondrial and Y-DNA mutations, ideal for expert-level genetic genealogists.
  • 🌐 23andMe provides both genealogy and health reports, with ongoing research updates and a list of relative matches.
  • 🏞️ Ancestry.com focuses on ancestry with a detailed ethnicity report and a large database, particularly useful for North Americans.
  • 🌟 MyHeritage is a cost-effective option for genealogy, with a strong focus on European records and Jewish ancestry, and also offers relative matches.
  • 😺 The presenter also mentions a DNA test for cats, indicating a niche market for DNA testing beyond human ancestry and health.
Q & A
  • What is the primary focus of CircleDNA?

    -CircleDNA is primarily focused on health-related information and provides detailed health information, including health risks for hereditary cancers and other conditions.

  • What is the price range for CircleDNA's DNA tests?

    -CircleDNA's basic service costs $189, and their premium service costs $629.

  • How can one receive a discount on CircleDNA tests?

    -Discounts are often available around holidays, and a special deal for viewers of the video is mentioned with a discount code MATTB33, which provides 33% off any of their tests.

  • What are the two general methods of DNA collection used by the kits?

    -The two general methods are using a swab that you rub against the inside of your cheek or spitting into a vial, with the latter generally taking longer and being a bit more difficult.

  • What is the importance of registering the sample with the company?

    -Registering the sample is extremely important because if this step is skipped, the company won’t know which sample belongs to the individual, which could lead to incorrect results.

  • What does CircleDNA test for regarding health risks?

    -CircleDNA checks for health risks for 36 hereditary cancers and 79 other conditions, and also tests to see if an individual is a carrier for 163 hereditary conditions.

  • What is the significance of mitochondrial DNA and Y-DNA tests?

    -Mitochondrial DNA tests can provide information about a person's matrilineal line and can go back tens of thousands of years in history. Y-DNA tests provide information about a person's patrilineal line, tracing back through the father's side.

  • How does 23andMe differ from other tests in terms of offerings?

    -23andMe offers both genealogy and health reports. It provides an ethnicity estimate, a list of relative matches, and haplogroup results at no extra charge.

  • What is unique about Ancestry.com's ethnicity report?

    -Ancestry.com's ethnicity report is more detailed, especially for North Americans, because they have the largest database of users, allowing for a more precise breakdown of where one's ancestors came from.

  • What are the benefits of using Ancestry.com for building a family tree?

    -Ancestry.com has a user-friendly interface designed for building family trees and provides access to millions of online records, which can be particularly helpful for genealogical research.

  • Why might someone choose MyHeritage over Ancestry.com?

    -MyHeritage might be preferred by those who are Jewish or live outside of North America, as it has a stronger focus on European records and offers competitive pricing.

  • What is the general advice given for choosing a DNA test based on the script?

    -The choice of DNA test depends on the individual's interests and needs. For health information, CircleDNA is recommended. For genealogy, FamilyTreeDNA is suggested for experts, while MyHeritage or Ancestry is recommended for average users, with a preference for MyHeritage for those outside North America or of Jewish descent. For a balance of health and genealogy information, 23andMe is suggested.

Outlines
00:00
🧬 DNA Testing for Genealogy and Health Insights

Matt Baker introduces the topic of DNA testing, focusing on its utility for genealogy enthusiasts looking to construct their family trees. He mentions having taken five different DNA tests and plans to compare them, showing the results for each. Baker discloses receiving some kits for free but assures viewers he will maintain an unbiased perspective. The five DNA test kits reviewed are CircleDNA, FamilyTreeDNA, Ancestry.com, 23andMe, and MyHeritage, which are discussed in order of their price, starting with the most expensive. CircleDNA, the costliest at $189 for basic and $629 for premium services, is highlighted for its focus on health-related information and being marketed as the 'World’s Most Comprehensive DNA Test.' Baker also notes that discounts are often available around holidays and provides a special deal for viewers. The video outlines the two primary methods of DNA sample collection and emphasizes the importance of not eating, drinking, or brushing teeth before testing. The process for registering the sample and mailing it back to the company is described, followed by the waiting period for results, which can take several weeks.

05:04
📊 In-Depth Look at CircleDNA's Health and Ancestry Reports

The summary of CircleDNA's results is presented, emphasizing the premium version's extensive health risk assessment for hereditary cancers and other conditions. Baker reveals being at a higher risk for Type-2 diabetes, which aligns with his family history. The report also identifies him as a carrier for certain hereditary conditions, particularly highlighting risks for heavy smokers. Additionally, the report covers personal drug responses to 103 FDA-approved drugs. For genealogy, CircleDNA provides an ancestry report, which Baker finds basic and not entirely accurate. The video also touches on the 'fun' aspects of the test, listing various personal traits and predispositions, from taste sensitivity to intelligence. Despite the comprehensive health information, Baker concludes that genetics is not destiny and stresses the importance of lifestyle choices.

10:09
👪 FamilyTreeDNA: Autosomal, Mitochondrial, and Y-DNA Testing

FamilyTreeDNA is introduced as a more affordable option at $80 for basic testing, with additional costs for more detailed reports. The video explains the concepts of autosomal DNA, mitochondrial DNA, and Y-chromosome DNA. Autosomal DNA provides a broad view of one's ancestry, while mitochondrial DNA and Y-DNA offer insights into matrilineal and patrilineal lines, respectively. FamilyTreeDNA's ancestry report is more detailed than CircleDNA's, although Baker still finds some discrepancies in the results. The value of relative matches for those with limited family history knowledge is discussed, as well as the process of reaching out to potential relatives. The video also covers the concept of haplogroups and how they can trace one's lineage back tens of thousands of years. FamilyTreeDNA is praised for its in-depth information on mutations, making it a preferred choice for those seriously interested in genetic genealogy.

15:15
🌐 23andMe: A Combination of Genealogy and Health Reporting

23andMe is presented as a unique option offering both genealogy and health reports. The genealogy report includes an ethnicity estimate and a list of relative matches, with haplogroup results provided at no extra charge. Baker mentions having previously discussed 23andMe in a 2019 video and provides a link for more information. The health results from 23andMe are less comprehensive than CircleDNA but still cover a range of genetic diseases and additional interesting traits. The company is noted for continuously updating its research, offering new reports over time.

20:18
🏡 Ancestry.com and MyHeritage: Focus on Ancestry with Additional Features

Ancestry.com and MyHeritage are compared, both offering ancestry-focused tests without health information. Ancestry.com stands out for its detailed ethnicity reports and large user database, particularly beneficial for North Americans. The video discusses the discovery of a previously unknown first cousin through Ancestry's relative matching feature. MyHeritage is noted as the least expensive option and is highlighted for its appeal to those from Europe or with Jewish ancestry. Both platforms provide tools for building family trees and offer access to extensive online records with a paid membership. Baker concludes by stating that the best test depends on individual interests and circumstances, recommending CircleDNA for health information, FamilyTreeDNA for expert genealogists, MyHeritage or Ancestry for general genealogy within specific regions, and 23andMe for a balance of health and genealogy information.

Mindmap
Keywords
💡DNA tests
DNA tests are a method used to analyze an individual's genetic material to determine ancestry, health risks, and other genetic traits. In the video, Matt Baker discusses various DNA tests, emphasizing their utility in genealogy and health information. The tests are used to build family trees and understand one's genetic health risks.
💡Genealogy
Genealogy is the study of family history and lineage. In the context of the video, it refers to the use of DNA tests to trace one's ancestry and construct a family tree. The video highlights how DNA tests can provide insights into a person's ethnic origins and connect them with relatives.
💡CircleDNA
CircleDNA is a DNA testing service that focuses on providing comprehensive health-related genetic information. It is mentioned as one of the most expensive options but offers detailed health insights. In the video, Matt Baker took the CircleDNA test and received information on health risks, carrier status for certain conditions, and drug responses.
💡Autosomal DNA
Autosomal DNA refers to the genetic material found in the non-sex chromosomes, which are inherited from both parents. The video explains that autosomal DNA tests can provide a broad view of an individual's ancestry, making up approximately 50% from each parent and offering a snapshot of the entire family tree.
💡Mitochondrial DNA
Mitochondrial DNA (mtDNA) is genetic information found in the mitochondria of cells, which is inherited solely from the mother. The video discusses how mtDNA tests can trace a person's matrilineal ancestry, offering insights into ancient maternal lineage through haplogroups.
💡Y-chromosome DNA
Y-chromosome DNA (Y-DNA) is genetic information found on the Y chromosome, which is passed from father to son. In the video, it is explained that Y-DNA tests can reveal information about a person's patrilineal ancestry. It is used to trace the direct male line and is particularly useful for males to explore their father's side of the family.
💡Haplogroups
Haplogroups are groups of genetic markers that indicate a person's ancestral lineage. In the context of the video, haplogroups are used to identify the genetic lineage to which an individual belongs, based on Y-DNA or mtDNA. They are used to trace ancient ancestry and are labeled with alphabetic codes.
💡Relative matches
Relative matches refer to other individuals in a DNA testing database who share DNA with the person taking the test. The video mentions that services like FamilyTreeDNA and 23andMe provide lists of relative matches, which can help individuals discover unknown relatives and build their family trees.
💡Ethnicity estimates
Ethnicity estimates are provided by DNA testing services to give an individual an idea of their ancestral origins based on their genetic makeup. The video discusses how companies like Ancestry.com offer detailed ethnicity reports, breaking down the regions from which an individual's ancestors likely hailed.
💡Health risks
Health risks, as discussed in the video, are genetic predispositions to certain diseases that can be identified through DNA testing. CircleDNA, for instance, checks for health risks related to hereditary cancers and other conditions, providing individuals with insights into their potential health challenges.
💡Carrier status
Carrier status indicates that an individual carries a gene for a particular genetic disorder but does not necessarily exhibit symptoms of the disorder. In the video, Matt Baker found out that he is a carrier for a gene that could be dangerous for heavy smokers, which is important information for personal and family health planning.
Highlights

Matt Baker discusses DNA tests for genealogy and family tree building.

Compares five DNA tests: CircleDNA, FamilyTreeDNA, Ancestry.com, 23andMe, and MyHeritage.

CircleDNA provides the most detailed health information of any tested kit, with a focus on health-related data.

DNA test kits often offer discounts around holidays, with potential savings of 30 to 40%.

CircleDNA offers a special deal for viewers with a 33% discount using the code MATTB33.

Two common DNA collection methods are swabbing the cheek and spitting into a vial.

It's important not to eat, drink, or brush teeth 30 minutes before taking a DNA test.

CircleDNA's premium service includes health risk assessments for hereditary cancers and conditions.

DNA tests can provide insights into ancestry, health risks, and personal traits.

FamilyTreeDNA offers detailed reports on autosomal, mitochondrial, and Y-DNA for genealogy enthusiasts.

23andMe provides both genealogy and health reports, with ongoing research updates.

Ancestry.com stands out for its detailed ethnicity reports and large database for North American users.

MyHeritage is the least expensive test and offers a good option for those outside North America or with Jewish ancestry.

Ancestry and MyHeritage both offer tools to build family trees and access to online records with a membership.

Taking a DNA test can reveal unexpected family connections or surprises about one's lineage.

Matt Baker discovered a previously unknown first cousin through DNA testing.

The choice of DNA test depends on the individual's interests in health information or genealogy.

Upcoming video will feature a DNA test for cats, highlighting Matt's personal interest as a cat owner.

Transcripts
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