Acute Kidney Injury (Acute Renal Failure) Nursing NCLEX Review Management, Stages, Pathophysiology

RegisteredNurseRN
15 Jul 201727:42
EducationalLearning
32 Likes 10 Comments

TLDRThe video script provides an in-depth review of acute kidney injury (AKI), also known as acute renal failure, which is characterized by a sudden decrease in renal function leading to the accumulation of waste products like urea and creatinine in the blood. The video outlines three primary causes of AKI: pre-renal, intra-renal, and post-renal, each associated with different conditions such as cardiac issues, drug toxicity, and urinary blockages. It emphasizes the importance of early detection and treatment to prevent chronic renal failure. The script also discusses the stages of AKI, including the initiation, oliguric, diuretic, and recovery stages, detailing the signs, symptoms, and nursing interventions for each. It highlights the significance of monitoring lab values like blood urea nitrogen (BUN) and creatinine levels, as well as the role of dialysis in treating severe cases. The video concludes with a quiz to test the viewer's understanding of AKI.

Takeaways
  • 🚨 Acute kidney injury (AKI) is a sudden decrease in renal function that can lead to a buildup of waste products like urea and creatinine in the blood.
  • ⏳ AKI can be reversible if caught early and treated properly, but if not addressed, it can progress to chronic renal failure.
  • πŸ“ Causes of AKI are categorized into pre-renal (before the kidney), intra-renal (within the kidney), and post-renal (after the kidney) issues.
  • πŸ’“ Pre-renal injury often stems from cardiac issues, bleeding, dehydration, or burns that reduce blood flow to the kidneys.
  • πŸ’Š Intra-renal injury can be caused by nephrotoxic drugs, severe infections, or direct kidney injuries.
  • 🚫 Post-renal causes involve blockages in the urinary system, such as renal calculi or an enlarged prostate, which obstruct urine flow.
  • πŸ§ͺ Lab tests like blood urea nitrogen (BUN), creatinine levels, and glomerular filtration rate (GFR) are crucial for diagnosing AKI.
  • πŸ“‰ A decreased GFR indicates that the kidneys are not filtering blood properly, which can result in oliguria (low urine output) or polyuria (high urine output).
  • 🌑️ Metabolic acidosis and electrolyte imbalances, including hyperkalemia, are common complications of AKI that need careful monitoring and management.
  • πŸ’§ Fluid management is critical, with patients needing restrictions to prevent overloading or underfilling due to the kidneys' impaired function.
  • πŸ”„ The stages of AKI include initiation, oliguria, diuresis, and recovery, with the duration and outcomes varying based on the severity and treatment.
  • ⏳ The recovery stage can take over a year and may not be reached by all patients, with some progressing to chronic kidney disease instead.
Q & A
  • What is acute kidney injury?

    -Acute kidney injury is a sudden decrease in renal function where the kidneys are unable to filter the blood properly, leading to a buildup of waste products like urea and creatinine in the blood.

  • How can acute kidney injury be classified based on its location in the body?

    -Acute kidney injury can be classified into pre-renal, intra-renal, and post-renal causes. Pre-renal issues occur before the kidney (e.g., decreased blood flow due to cardiac issues), intra-renal issues are within the kidney (e.g., damage to nephrons due to toxic drugs), and post-renal issues occur after the kidney (e.g., blockage in the urinary system).

  • What is the role of the nephrons in the kidney?

    -Nephrons are the functional units of the kidney, responsible for filtering the blood, reabsorbing nutrients, and creating urine filtrate, which is then voided through the bladder and urethra.

  • What is the significance of creatinine in assessing kidney function?

    -Creatinine is a waste product from muscle breakdown that is solely filtered by the kidneys. Its level in the blood, along with creatinine clearance and glomerular filtration rate (GFR), helps determine how well the kidneys are filtering and removing waste from the body.

  • What are the normal ranges for creatinine clearance and GFR?

    -The normal range for creatinine clearance is 85 to 125 mL/min for females and 95 to 140 mL/min for males. A normal GFR should be 90 mL/min or higher.

  • What happens to a patient's urinary output and waste levels when GFR is decreased?

    -When GFR is decreased, the patient's urinary output will decrease, often to less than 400 mL per day. Waste levels such as BUN and creatinine will increase due to the reduced filtering capacity of the kidneys.

  • What are the three stages of acute kidney injury?

    -The three stages of acute kidney injury are the initiation stage, oliguric stage, and diuretic stage. The initiation stage is when the injury begins, the oliguric stage is characterized by decreased urine output and increased waste levels, and the diuretic stage involves the nephrons recovering and increasing urine output.

  • What is the importance of monitoring a patient's electrolyte levels during acute kidney injury?

    -Monitoring electrolyte levels is crucial because impaired kidney function can lead to imbalances such as hyperkalemia (high potassium levels), which can cause cardiac issues, or hypokalemia (low potassium levels), which can occur during the diuretic stage as the kidneys start to filter more but cannot yet concentrate urine properly.

  • What nursing interventions are important during the oliguric stage of acute kidney injury?

    -Nursing interventions during the oliguric stage include monitoring fluid intake and output, daily weights, blood pressure, lung sounds for signs of pulmonary edema, and oxygen saturation. It's also important to limit protein consumption, restrict potassium-rich foods, and monitor for signs of hyperkalemia.

  • What is the expected duration of the diuretic stage in acute kidney injury?

    -The diuretic stage can last anywhere from a week to three weeks, during which the patient may produce a large amount of urine due to the recovery of the nephrons' filtering ability.

  • What is the final stage of acute kidney injury and what are its characteristics?

    -The final stage is the recovery stage, which begins when the GFR returns to normal. At this point, the patient's urinary output, BUN and creatinine levels, and electrolytes should normalize, indicating that the kidneys have recovered from the acute injury.

Outlines
00:00
πŸ˜€ Introduction to Acute Kidney Injury

The video begins with an introduction to acute kidney injury (AKI), also known as acute renal failure. It explains that AKI is characterized by a sudden decrease in renal function, leading to the accumulation of waste products like urea and creatinine in the blood. The kidneys' inability to filter blood properly also results in fluid buildup. The video emphasizes that AKI can be reversible if caught early and treated correctly. It outlines three main causes of AKI based on their location: pre-renal, intra-renal, and post-renal causes. Pre-renal causes are associated with issues before the kidney, such as heart problems, bleeding, dehydration, and burns, which can lead to decreased blood flow to the kidneys.

05:01
πŸ”¬ Understanding the Nephron and Internal Causes of AKI

This paragraph delves into the structure and function of the nephron, the basic filtering unit of the kidney. It describes the renal corpuscle, which includes the glomerulus and Bowman's capsule, and the renal tubule, which is responsible for reabsorbing nutrients and regulating electrolyte balance. The paragraph explains that internal kidney injury can occur due to damage to the nephron, which can be caused by nephrotoxic drugs, infections, or other kidney injuries. It also discusses post-renal causes of AKI, which involve blockages in the urinary system after the kidneys, such as renal calculi or an enlarged prostate, leading to urine retention and decreased kidney function.

10:03
πŸ§ͺ Lab Tests and Diagnosing Acute Kidney Injury

The video explains the importance of lab tests in diagnosing AKI. It covers the significance of creatinine levels, which are used to measure kidney function. Creatinine is filtered by the glomerulus, and its levels in the blood can indicate how well the kidneys are functioning. The paragraph also discusses creatinine clearance and the glomerular filtration rate (GFR), which are used to assess the kidney's ability to filter waste from the blood. The video highlights the signs and symptoms that may be present when GFR is decreased, such as decreased urinary output, fluid retention, and increased levels of waste products and electrolyte imbalances.

15:03
πŸ₯ Nursing Care for Patients with Acute Kidney Injury

This section focuses on the nursing care for patients with AKI. It discusses the importance of monitoring urinary output, as patients in the oliguric stage of AKI may produce less than 400 milliliters of urine per day. The video advises on nursing interventions, such as limiting protein intake, monitoring for hyperkalemia and its cardiac effects, and ensuring patient safety due to potential neurologic changes. It also covers the need to monitor fluid balance, blood pressure, lung sounds, and oxygen saturation, as well as the importance of dialysis in treating severe cases of AKI.

20:05
πŸ“ˆ Stages of Acute Kidney Injury and Patient Monitoring

The video outlines the stages of AKI, starting with the initiation stage, where the kidney becomes injured and the signs and symptoms begin to appear. It emphasizes the need to identify and treat the cause promptly to prevent chronic renal failure. The oliguric stage is characterized by a decrease in urinary output and an increase in waste products like BUN and creatinine. The patient may experience neurologic changes, hyperkalemia, and fluid overload. The diuretic stage follows, where the kidneys start to recover and the patient begins to produce a large amount of urine due to osmotic diuresis. Finally, the recovery stage is marked by the return of normal GFR and urinary output, although this can take a year or more and may not be reached by all patients.

25:07
πŸ“ Conclusion and Further Learning

The video concludes by summarizing the key points about AKI, including its causes, stages, and nursing interventions. It encourages viewers to take a quiz to test their understanding of the condition and to subscribe for more educational content. The video also mentions that chronic kidney disease will be discussed in a future lecture, providing continuity for those interested in further learning about renal health.

Mindmap
Keywords
πŸ’‘Acute Kidney Injury (AKI)
Acute Kidney Injury, also known as acute renal failure, is a sudden decrease in renal function where the kidneys are unable to filter the blood effectively. This leads to a buildup of waste products like urea and creatinine in the blood. It is a critical condition that can be reversible if caught early and treated appropriately, which is central to the video's educational theme on renal health.
πŸ’‘Pre-Renal Causes
Pre-renal causes refer to conditions that affect the blood flow to the kidneys, originating from issues before the kidney such as the renal artery or heart problems. In the script, it is mentioned that cardiac issues, bleeding, dehydration, and burns can lead to decreased perfusion to the kidneys, causing pre-renal injury.
πŸ’‘Intra-Renal Causes
Intra-renal causes pertain to damage within the kidney itself, such as damage to the nephrons, which are the functional units of the kidney responsible for filtering blood and producing urine. The script discusses how nephrotoxic drugs, infections, and injuries can cause intra-renal injury and affect kidney function.
πŸ’‘Post-Renal Causes
Post-renal causes involve blockages in the urinary system after the kidneys, which can prevent urine from draining out of the system. This can lead to a buildup of pressure in the kidneys and decreased kidney function. The script mentions renal calculi (kidney stones) and an enlarged prostate as examples of post-renal causes.
πŸ’‘Creatinine
Creatinine is a waste product from muscle breakdown that is filtered out by the kidneys. A normal creatinine level is 0.6 to 1.2 milligrams per deciliter. In the context of the video, elevated creatinine levels indicate decreased kidney function, making it a critical biomarker for diagnosing and monitoring AKI.
πŸ’‘Glomerular Filtration Rate (GFR)
Glomerular Filtration Rate is a measure of how well the kidneys are filtering the blood. A normal GFR is 90 milliliters per minute or higher. The video emphasizes the importance of GFR in assessing kidney function, as a decreased GFR signifies impaired kidney function and is a key indicator in diagnosing AKI.
πŸ’‘Blood Urea Nitrogen (BUN)
Blood Urea Nitrogen is a measure of the amount of urea, a waste product from protein breakdown in the liver, in the blood. A normal BUN level is 6 to 20 milligrams per deciliter. The video script explains that high BUN levels are indicative of AKI, as the kidneys are not effectively filtering out this waste product.
πŸ’‘Oliguria
Oliguria refers to a decreased urinary output, typically less than 400 milliliters per day. In the video, oliguria is a symptom of AKI during the oliguric phase, where the kidneys' ability to filter blood is significantly reduced, leading to a buildup of waste products in the body.
πŸ’‘Diuresis
Diuresis is a phase in the recovery from AKI where the patient begins to produce a large amount of urine, about 3 to 6 liters per day. This occurs as the kidneys start to recover and filter out the accumulated waste products, but are not yet able to concentrate the urine properly. The video describes diuresis as a sign of improving kidney function.
πŸ’‘Metabolic Acidosis
Metabolic acidosis is a condition resulting from the buildup of acidic substances in the body due to decreased excretion by the kidneys. The video explains that in AKI, the impaired kidney function leads to a decrease in the excretion of hydrogen ions, causing the blood to become more acidic and the patient to experience symptoms like confusion and rapid, deep breathing.
πŸ’‘Electrolyte Imbalances
Electrolyte imbalances occur when there is an abnormal level of electrolytes in the body, which can result from kidney dysfunction. The video discusses how AKI can lead to high potassium levels (hyperkalemia) due to decreased excretion, and later to low potassium levels (hypokalemia) during the diuresis phase as the kidneys start to filter but lose excess potassium.
Highlights

Acute kidney injury (AKI) is characterized by a sudden decrease in renal function leading to the accumulation of waste products like urea and creatinine in the blood.

AKI can be reversible if caught early and treated appropriately, highlighting the importance of prompt diagnosis and intervention.

There are three primary causes of AKI: pre-renal, intra-renal, and post-renal, each with distinct mechanisms and implications for treatment.

Pre-renal AKI is often caused by decreased blood flow to the kidneys, such as from cardiac issues, bleeding, dehydration, or burns.

Intra-renal AKI involves damage to the nephrons within the kidney, which can be caused by nephrotoxic drugs, severe infections, or kidney injuries.

Post-renal AKI is caused by blockages in the urinary system after the kidneys, such as from renal calculi or an enlarged prostate.

Creatinine levels and glomerular filtration rate (GFR) are key indicators used to assess kidney function and diagnose AKI.

A normal GFR should be 90 mL/min or higher, and deviations from this can indicate impaired kidney function.

Patients with decreased GFR may exhibit symptoms such as oliguria (low urine output), fluid retention, and electrolyte imbalances.

Hyperkalemia, or high potassium levels, is a serious complication that requires close monitoring and may necessitate medical intervention.

The stages of AKI include initiation, oliguria, diuresis, and recovery, each with specific clinical presentations and nursing interventions.

During the diuresis stage, patients may experience polyuria (high urine output) due to the kidneys' increased ability to filter blood.

Recovery from AKI can take over a year and depends on the extent of kidney damage, the duration of the oliguric stage, and the patient's age.

Some patients may not fully recover and can progress to chronic kidney disease, emphasizing the need for ongoing care and monitoring.

Nursing interventions are crucial throughout all stages of AKI, focusing on monitoring and managing symptoms, fluid and electrolyte balance, and patient safety.

Dialysis may be required for severe cases of AKI, where it replaces the kidney's function by filtering waste and excess fluid from the blood.

Educational resources, such as quizzes and subscription to relevant channels, are available to enhance understanding and knowledge of AKI and its management.

Transcripts
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